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Cat. No.	Product Name	Target	Signaling Pathways
T3470	Cis-ACBD cis-1-aminocyclobutane-1,3-dicarboxylic acid,氨基二羧酸	Amino Acids and Derivatives	Metabolism
	Cis-ACBD (cis-1-aminocyclobutane-1,3-dicarboxylic acid) 是一种有效的选择性 N-甲基-D-天冬氨酸受体激动剂。
T21469	Cyclopenthiazide Cyclomethiazide,Su-8341,SU 8341,环戊噻嗪	Others	Others
	Cyclopenthiazide (Cyclomethiazide) 是一种噻嗪类利尿剂，用于治疗高血压和心力衰竭。减少钙离子和尿酸的排泄，增加钠和钾离子的排泄。
T0796	Prilocaine hydrochloride Prilocaine HCl,Propitocaine hydrochloride,Xylonest,盐酸丙胺卡因	ATPase; Sodium Channel	Membrane transporter/Ion channel
	Prilocaine hydrochloride (Prilocaine HCl) 是一种氨基酰胺类局部麻醉剂，作用于神经元膜上的钠通道并限制癫痫发作的扩散。它是Na/K-ATPase 抑制剂，具有神经毒性作用。
T0018	Procainamide hydrochloride Procapan,Procainamide HCl,Pronestyl,Procanbid,盐酸普鲁卡因胺	DNA Methyltransferase; Sodium Channel; AChR; Autophagy	Autophagy; Chromatin/Epigenetic; Membrane transporter/Ion channel; Neuroscience
	Procainamide hydrochloride (Procapan) 是一种用于研究心律失常的抗心律失常制剂。
T0030	Bupivacaine hydrochloride Vivacaine,Bupivacaine HCl,盐酸布比卡因	Sodium Channel	Membrane transporter/Ion channel
	Bupivacaine hydrochloride (Vivacaine) 是NMDA 受体抑制剂，可用于慢性疼痛的研究。它可阻断钠、L-钙和钾通道，还阻断SCN5A 通道，IC50为 69.5 μM。
T1756	Ilaprazole sodium IY-81149 sodium,艾普拉唑钠	Proton pump; TOPK	MAPK; Membrane transporter/Ion channel
	Ilaprazole sodium (IY-81149 sodium) 是一种具有口服活性质子泵抑制剂，以剂量依赖性方式不可逆地抑制 H+/K+-ATPase，在兔壁细胞制剂中的 IC50为 6 μM。它也是一种有效的 T 细胞起源蛋白激酶(TOPK)抑制剂，用于胃溃疡的研究。
T2189	Sodium orthovanadate Sodium vanadate,钒酸钠,Trisodium vanadate,Sodium pervanadate	ATPase; Phosphatase	Membrane transporter/Ion channel; Metabolism
	Sodium orthovanadate 是一种蛋白酪氨酸磷酸酶，碱性磷酸酶和一些ATP 酶的抑制剂，有可能充当磷酸盐类似物。它具有胰岛素样作用、对心室肌的正性肌力作用和其他代谢作用。
T0866	Propafenone Rythmol,普罗帕酮,Propafenonum	Potassium Channel; MRP; Sodium Channel	Immunology/Inflammation; Membrane transporter/Ion channel
	Propafenone (Propafenonum) 是钠通道阻滞剂，它对 β 受体具有高亲和力 (IC50=32 nM)。它能够阻断瞬时外向钾电流 (Ito) (IC50: 4.9 nM) 和持续延迟整流器K+电流 (Isus) (IC50: 8.6 nM) ，具有抗心律失常的作用。它能够诱导线粒体功能障碍及诱导细胞凋亡，从而抑制食管癌增殖。
T0378L	Oxybuprocaine Butoxyprocaine,BNX,Benoxinate,Novescine,Novesin
	Oxybuprocaine is an ester-type local anesthetic that is used especially in ophthalmology and otolaryngology. Oxybuprocaine binds to sodium channels and reversibly stabilizes the neuronal membrane which decreases its permeability to sodium ions.
T35842	5-chloro Hydrochlorothiazide
	5-chloro Hydrochlorothiazide is a derivative of hydrochlorothiazide, which is a diuretic and antihypertensive agent that increases renal excretion of sodium, potassium, chloride, and bicarbonate ions by inhibiting tubular reabsorptive mechanisms.
T81067	Sulfo-Cy3(Me)COOH sodium
	Sulfo-Cy3(Me)COOH sodium 为含磺酸根离子的 Cy3（Cyanine3）染料衍生物，而 Trisulfo-Cy3-acid disodium 含 sulfonate （磺酸根离子），水溶性更佳。
T22014	8-CPT-2Me-cAMP, sodium salt
	8-CPT-2Me-cAMP sodium is a sodium salt compound that selectively activates exchange proteins activated by cAMP (Epac). These Epac proteins are cAMP-sensitive guanine nucleotide exchange factors (GEFs) responsible for activating small GTPases Rap1 and Rap2. 8-CPT-2Me-cAMP sodium specifically activates Epac1 with an EC50 value of 2.2 μM, while showing no activation of PKA with an EC50 value greater than 10 μM [1]. Additionally, 8-CPT-2Me-cAMP sodium stimulates the Epac-mediated release of calcium ...
T83943	ING-2 AM
	ING-2 AM是一种能透过细胞膜的荧光钠离子(Na+)指示剂，与钠结合(Kd=20 mM)。激发和发射峰值(λ)分别为525 nm和545 nm。该化合物对K+离子具有20倍的选择性。在体外和原位实验中用于检测实时的钠流入。
T83944	IPG-4 AM
	IPG-4 AM 是一种可渗透膜的荧光钾离子 (K+) 指示剂，具有与钾结合的特性 (Kd= 7 mM)。其激发和发射峰值 (λ) 分别为 525 和 545 nm。它对 K+ 比 Na+ 离子具有 100:1 的选择性。可用于实时检测细胞内 K+ 的变化，也用于监测体内外 K+ 的变化。
T35731	Deethylindanomycin
	Deethylindanomycin is a polyether antibiotic that has been found in S. setonii. It is active against a variety of Gram-positive bacteria, including various strains of S. aureus and Streptococcus, as well as one strain of S. pneumoniae (MICs = 4, 4, and 2 μg/ml, respectively). It is also active against coccidia in vitro, inhibiting E. tenella development, but is inactive against E. tenella infection in chicks when administered at a dose of 200 μg/g in the diet. Deethylindanomycin acts as an ionop...
T62272	TRPC6-IN-3
	TRPC6-IN-3 (compound 17) 是一种口服具有活力的瞬时受体电位 C6 离子通道 (TRPC6) 抑制剂。TRPC6-IN-3 能够调节细胞内钙浓度，也能够调节包括钙离子和钠离子在内的阳离子通量来调节膜电位。TRPC6-IN-3 可以用于研究呼吸系统。
T37052	Tetranactin
	Tetranactin is a macrotetrolide and a monovalent cation ionophore that has been found in S. aureus and has antibacterial, insecticidal, and mitogenic activities. It exhibits an equilibrium permeability ratio 1,000-fold greater for lithium than sodium or cesium ions accross bilayer membranes at low voltages. Tetranactin inhibits the growth of Gram-positive bacteria and C. miyabeanus and R. solani fungi when used at concentrations less than 0.9 μg/ml. Tetranactin (0.5-1.5 μg per insect) dose-depen...

化合物

Cat.No: T3470

Synonym: cis-1-aminocyclobutane-1,3-dicarboxylic acid,氨基二羧酸

Target: Amino Acids and Derivatives

Cyclopenthiazide

Cat.No: T21469

Synonym: Cyclomethiazide,Su-8341,SU 8341,环戊噻嗪

Target: Others

Prilocaine hydrochloride

Cat.No: T0796

Synonym: Prilocaine HCl,Propitocaine hydrochloride,Xylonest,盐酸丙胺卡因

Target: ATPase, Sodium Channel

Procainamide hydrochloride

Cat.No: T0018

Synonym: Procapan,Procainamide HCl,Pronestyl,Procanbid,盐酸普鲁卡因胺

Target: DNA Methyltransferase, Sodium Channel, AChR, Autophagy

Bupivacaine hydrochloride

Cat.No: T0030

Synonym: Vivacaine,Bupivacaine HCl,盐酸布比卡因

Target: Sodium Channel

Ilaprazole sodium

Cat.No: T1756

Synonym: IY-81149 sodium,艾普拉唑钠

Target: Proton pump, TOPK

Sodium orthovanadate

Cat.No: T2189

Synonym: Sodium vanadate,钒酸钠,Trisodium vanadate,Sodium pervanadate

Target: ATPase, Phosphatase

Cat.No: T0866

Synonym: Rythmol,普罗帕酮,Propafenonum

Target: Potassium Channel, MRP, Sodium Channel

Cat.No: T0378L

Synonym: Butoxyprocaine,BNX,Benoxinate,Novescine,Novesin

5-chloro Hydrochlorothiazide

Cat.No: T35842

Sulfo-Cy3(Me)COOH sodium

Cat.No: T81067

8-CPT-2Me-cAMP, sodium salt

Cat.No: T22014

Cat.No: T83943

Cat.No: T83944

Deethylindanomycin

Cat.No: T35731

Cat.No: T62272

Cat.No: T37052

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